當(dāng)前位置 ： Millipore >>> Millipore/MAB5384 | Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody/MAB5384/100 µg
Millipore/MAB5384 | Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody/MAB5384/100 µg
  • Millipore/MAB5384 | Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody/MAB5384/100 µg

Millipore/MAB5384 | Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody/MAB5384/100 µg

價格: ￥4440.00 市場價: 7400.00
貨號: MAB5384
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品：無質(zhì)量問題不接受退換貨，下單前請仔細(xì)核對信息。
下單后請及時聯(lián)系客服核對商品價格，訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費服務(wù)熱線

4000-520-616

  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價
  • 品質(zhì)甄選 正品保證
  • 嚴(yán)控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumberMAB5384
      BrandFamilyChemicon®
      TradeName
      • Chemicon
      DescriptionAnti-NG2ChondroitinSulfateProteoglycanAntibody
      BackgroundInformationNG2isahighmolecularweight,integralmembranechondroitinsulfateproteoglycan.Itisfoundonthesurfacesofanunusualclassofglialcellswithinthedevelopingandmaturecentralnervoussystemthathavethepropertiesofoligodendrocyteprecursorcells(i.e.,O-2AProgenitorcells).NG2isalsofoundonthesurfacesofchondroblasts,proliferatingcapillaryendothelialcells,somehumanmelanomacelllines,andonleukemicblastsinchildhoodacutelymphoblasticleukemia.TheNG2proteoglycanislikelytoplayaroleinregulationofcellmotility,axonoutgrowthandthecellularresponsestoplatelet-derivedgrowthfactor.
      ProductInformation
      FormatPurified
      Control
      • Neonatalratbrainextract
      PresentationLiquidin0.02MPhosphatebuffer,containing0.25MNaCland0.1%azide.
      StorageandShippingInformation
      StorageConditionsStablefor1yearatfromdateofreceipt.
      Applications
      ApplicationAnti-NG2ChondroitinSulfateProteoglycanAntibodydetectslevelofNG2ChondroitinSulfateProteoglycan&hasbeenpublished&validatedforuseinWB,IC,ELISA,IH.
      KeyApplications
      • WesternBlotting
      • Immunocytochemistry
      • ELISA
      • Immunohistochemistry
      ApplicationNotesImmunocytochemistry:1:200-1:500dilutionofapreviouslotwasusedonoligodendrocyteprecursorcells.

      ELISA(direct):ApreviouslotofthisantibodywasusedinELISA.

      Optimalworkingdilutionsmustbedeterminedbyenduser.
      BIOLOGicalInformation
      ImmunogenCelllineexpressingatruncatedformofNG2.
      Clone132.39
      ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
      HostMouse
      SpecificityNG2ChondroitinSulfateProteoglycan.MAB5384reactswithnative,recombinantandproteinfromcellswhichexpressNG2.
      IsotypeIgG1
      SpeciesReactivity
      • Human
      • Mouse
      • Rat
      SpeciesReactivityNoteRat.Expectedtoreactwithhumanandmousebasedonsequencesimilarity.
      AntibodyTypeMonoclonalAntibody
      EntrezGeneNumber
      EntrezGeneSummaryextracellularmatrixproteinsecretedbymanycelltypes;memberofthelargechondroitinsulfateproteoglycan(CSPG)family;maybeinvolvedwithangiogenesis-dependentprocessessuchaswoundhealingortumorgrowth[RGD]
      GeneSymbol
      • CSPG4
      • MSK16
      • MCSP
      • NG2
      • MCSPG
      • MEL-CSPG
      • HMW-MAA
      PurificationMethodProteinGPurified
      UniProtNumber
      UniProtSummaryFUNCTION:Proteoglycanplayingaroleincellproliferationandmigrationwhichstimulatesendothelialcellsmotilityduringmicrovascularmorphogenesis.Mayalsoinhibitneuriteoutgrowthandgrowthconecollapseduringaxonregeneration.Cellsurfacereceptorforcollagenalpha2(VI)whichmayconfercellsABIlitytomigrateonthatsubstrate.BindsthroughitsextracellularN-terminusgrowthfactors,extracellularmatrixproteasesmodulatingtheiractivity.MayregulateMPP16-dependentdegradationandinvasionoftypeIcollagenparticipatinginmelanomacellsinvasionproperties.Maymodulatetheplasminogensystembyenhancingplasminogenactivationandinhibitingangiostatin.FunctionsalsoasasignaltransducingproteinbybindingthroughitscytoplasmicC-terminusscaffoldingandsignalingproteins.MaypromoteretractionfiberformationandcellpolarizationthroughRhoGTPaseactivation.Maystimulatealpha-4,beta-1integrin-mediatedadhesionandspreADIngbyrecruitingandactivatingasignalingcascadethroughCDC42,ACK1andBCAR1.MayactivateFAKandERK1/ERK2signalingcascades.

      SIZE:2326aminoacids;251909Da

      SUBUNIT:InteractswithGRIP1,GRIP2andGRIA2.FormsaternarycomplexwithGRIP1andGRIA2.InteractswithITGA4throughitschondroitinsulfateglycosaminoglycan.InteractswithBCAR1,CDC42andACK1.InteractswithMMP16(Bysimilarity).InteractswiththefirstPDZdomainofMPDZ.InteractswithPRKCA.InteractswithLGALS3andtheintegrincomposedofITGB1andITGA3.BindsTNC,laminin-1,COL5A1andCOL6A2.InteractswithPLGandangiostatin.BindsFGF2andPDGFA.

      SUBCELLULARLOCATION:Cellmembrane;Single-passtypeImembraneprotein;Extracellularside.Apicalcellmembrane;Single-passtypeImembraneprotein;Extracellularside.Cellprojection?lamellipodiummembrane;Single-passtypeImembraneprotein;Extracellularside.Note=Localizestotheplasmamembraneofoligodendrocytes(Bysimilarity).LocalizedattheapicalplasmamembraneitrelocalizestothelamellipodiaofastrocytomauponphosphorylationbyPRKCA.Localizestotheretractionfibers.Afractionmayundergocellsurfaceproteolysisandsecretion.

      TISSUESPECIFICITY:Neuralcellsandalsoextraneuraltissues,especiallyinthedevelopingmesenchyme.

      PTM:N-glycosylated(Bysimilarity).&O-glycosylated;containsglycosaminoglycanchondroitinsulfatewhicharerequiredforproperlocalizationandfunctioninstressfiberformation.InvolvedininteractionwithMMP16andITGA4.PhosphorylationbyPRKCAregulatesitssubcellularlocationandfunctionincellmotility.

      MISCELLANEOUS:ValuableMarkerforseveralincompletelydifferentiatedprecursorcells.
      MolecularWeight~280kDa
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188，秉承螞蟻淘一貫的嚴(yán)謹(jǐn)態(tài)度，由螞蟻淘公司專業(yè)人員負(fù)責(zé)品控、采購、物流、銷售、售后，保障正品優(yōu)質(zhì)。以“快速好省，為科研提供好產(chǎn)品、好價格”為理念，直接鏈接原廠家，從全國各地原制造商嚴(yán)格挑選188款科研精品，剔除品牌溢價，188生物新電商，把好的產(chǎn)品帶給科研！? 力求給你最優(yōu)質(zhì)的商品。
  • Q：生物188產(chǎn)品正品保障嗎？
    A：生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗，在業(yè)界享有良好的口碑；自營商城，直接從廠家采購， 自己的團(tuán)隊負(fù)責(zé)國際物流和清關(guān)，中間沒有第三方，所有流程嚴(yán)格把控，100%保證正品，假一罰十。

    Q：下單后可以修改訂單嗎？
    A：下單后的商品付款之前可以修改；訂單付款成功，需要聯(lián)系我們客服進(jìn)行修改；客服電話：4000-520-616

    Q：可以開發(fā)票嗎？
    A：本網(wǎng)站所售商品都是正規(guī)清關(guān)，均開具16%正規(guī)發(fā)票，發(fā)票金額含配送費金額，另有說明的除外。

    Q：商品幾天可以發(fā)貨？
    A：生物188商品，全部現(xiàn)貨銷售，付款后即可發(fā)貨,一般一周內(nèi)送達(dá)！

    Q：如何聯(lián)系商家？
    A：有任何問題夠可以電話咨詢我們，全國24小時免費服務(wù)熱線：4000-520-616 或聯(lián)系我們的在線客服QQ：1570468124

    Q：收到的商品少了/發(fā)錯了怎么辦？
    A：同個訂單購買多個商品可能會分為一個以上包裹發(fā)出，可能不會同時送達(dá)，建議查看訂單詳情是否是 部分發(fā)貨狀態(tài)；如未收到，可聯(lián)系在線客服或者致電4000-520-616。

    Q：退換貨/維修需要多長時間？
    A：一般情況下，退貨處理周期為客戶收到產(chǎn)品一個月內(nèi)（以快遞公司顯示簽收時間為準(zhǔn)），包裝規(guī)格、 數(shù)量、品種不符，外觀毀損、短缺或缺陷，請在收到貨24小時內(nèi)申請退換貨；特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴(yán)謹(jǐn)，我們僅銷售188款生物醫(yī)學(xué)科研用品，款款都是爆款；因為少所以聚焦，聚焦甄選每一款產(chǎn)品，聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號

獲取最新優(yōu)惠活動通知

  • 品質(zhì)甄選，正品保證

  • 自營電商，廠家直采

  • 極簡主義，188精品

友情鏈接：

公司版權(quán)所有 ? 2005-2021 蘇州螞蟻淘生物科技有限公司 蘇ICP備17049038號-10